Abstract
Lymphatic filarial nematodes remain a significant cause of morbidity throughout much of the tropics. One approach to the development of rational control methods is an improved understanding of the basic biology of these organisms in relation to the mechanisms used to complete their life cycles. In this article, Eileen Devaney, Sam Martin and Fiona Thompson review new approaches to defining stage-specific molecules in filarial nematodes, and discuss their recent work on the isolation and characterization of stage-regulated cDNAs from Brugia pahangi.
Original language | English |
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Pages (from-to) | 418-424 |
Number of pages | 7 |
Journal | Parasitology Today |
Volume | 12 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 1996 |
Keywords
- reactive surface-antigens
- heat-shock proteins
- Brugia-Pahangi
- messenger-RNA
- infective larvae
- differential display
- Malayi
- identification
- parasites
- microfilariae