Synthetic hydroxyapatite for bone-healing applications

I. R. Gibson*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)


This chapter reviews and discusses the clinical use of hydroxyapatite-containing implants, including their use as coatings and as bone graft substitutes (BGSs) in orthopedic, dental, and ophthalmic surgery. A strong focus is given to highlighting the low number of high-quality, Level I or II clinical trials carried out on these implants, despite the extensive period of use of many of these and also the vast range of medical devices used, both historically and currently. Additionally, the large number of variables in the physical and chemical properties of different hydroxyapatite coatings and BGSs need more consideration when understanding the clinical behavior of these implants.

Original languageEnglish
Title of host publicationHydroxyapatite (HAp) for Biomedical Applications
EditorsM Mucalo
PublisherWoodhead Publishing
Number of pages19
ISBN (Print)9781782420415, 9781782420330
Publication statusPublished - 27 Feb 2015


  • Bone graft substitutes (BGSs)
  • Clinical
  • Coatings
  • Dental
  • Hydroxyapatite (HAp)
  • Implants
  • Ophthalmology
  • Orthopedic


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