Abstract
The drug thalidomide has a notorious past. It was used between 1957-62 as a sedative and to treat morning sickness in early pregnancy but a serious side effect resulted in over 10,000 children born with severe birth defects.
How the drug caused these defects, which could affect most parts of the body and includes phocomelia – where the limbs are shortened and missing the long bones with the digits in some cases extruding from the shoulder or the hip – is becoming clearer.
How the drug caused these defects, which could affect most parts of the body and includes phocomelia – where the limbs are shortened and missing the long bones with the digits in some cases extruding from the shoulder or the hip – is becoming clearer.
Original language | English |
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Specialist publication | The Conversation |
Publisher | The Conversation UK |
Publication status | Published - 10 Dec 2015 |
Bibliographical note
Neil Vargesson receives or has received funding for thalidomide research from the Wellcome Trust, the Royal Society, University of Aberdeen, Imperial College London.Keywords
- Cancer
- India
- Brazil
- Thalidomide
- Crohn's disease
- Leprosy
- Thalidomide series