The impact of age, sex and morbidity count on early termination: a meta-analysis of individual patient data from clinical trials

J. S. Lees; P. Hanlon; E. Butterly; S. H. Wild; F. S. Mair; R. S. Taylor; B. Guthrie; K. Gillies; S. Dias; N. Welton; D. A. McAllister

doi:10.1093/ageing/afac126.021

The impact of age, sex and morbidity count on early termination: a meta-analysis of individual patient data from clinical trials

J. S. Lees, P. Hanlon, E. Butterly, S. H. Wild, F. S. Mair, R. S. Taylor, B. Guthrie, K. Gillies, S. Dias, N. Welton, D. A. McAllister

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Abstract

Multimorbidity is found in around half of people with any long-term condition but is substantially less common in randomised controlled trials (‘trials’). Multimorbidity may diminish a participant’s ability to complete a trial. However, empirical estimates of the association between individual patient characteristics and early termination are lacking.

Original language	English
Article number	963
Pages (from-to)	ii8
Number of pages	1
Journal	Age and Ageing
Volume	51
Issue number	Supplement 2
Early online date	14 Jun 2022
DOIs	https://doi.org/10.1093/ageing/afac126.021
Publication status	Published - 14 Jun 2022
Event	British Geriatrics Society Spring Meeting 2022 - Online event, United Kingdom Duration: 6 Apr 2022 → 8 Apr 2022 https://www.bgs.org.uk/events/2022-wales-spring-meeting

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Lees, J. S., Hanlon, P., Butterly, E., Wild, S. H., Mair, F. S., Taylor, R. S., Guthrie, B., Gillies, K., Dias, S., Welton, N., & McAllister, D. A. (2022). The impact of age, sex and morbidity count on early termination: a meta-analysis of individual patient data from clinical trials. Age and Ageing, 51(Supplement 2), ii8. Article 963. https://doi.org/10.1093/ageing/afac126.021

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AU - Guthrie, B.

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AU - Dias, S.

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The impact of age, sex and morbidity count on early termination: a meta-analysis of individual patient data from clinical trials

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