The importance of correction for tissue fraction effects in lung PET: Preliminary findings

T. Lambrou, A.M. Groves, K. Erlandsson, N. Screaton, R. Endozo, T. Win, J.C. Porter, B.F. Hutton

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

It has recently been recognized that PET/CT may play a role in diffuse parenchymal lung disease. However, interpretation can be confounded due to the variability in lung density both within and between individuals. To address this issue a novel correction method is proposed.
Original languageEnglish
Pages (from-to)2238-2246
Number of pages9
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume38
Issue number12
DOIs
Publication statusPublished - 2011

Bibliographical note

We acknowledge support for some scan costs and partial salary (T.L.) from GlaxoSmithKline (CRT115549). We also thank Dr. Pauline Lukey and Dr. Aiden Flynn (Fibrosis DPU, GSK) as well as the CRAFT Consortium for useful discussions. Also UCL/UCLH receives a portion of its research funding from the UK Department of Health’s NIHR Biomedical Research Centre funding scheme.

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