The prognosis of heart failure patients: Does sodium level play a significant role?

Tamrat Befekadu Abebe, Eyob Alemayehu Gebreyohannes, Yonas Getaye Tefera, Akshaya Srikanth Bhagavathula, Daniel Asfaw Erku, Sewunet Admasu Belachew, Begashaw Melaku Gebresillassie, Tadesse Melaku Abegaz

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Heart failure (HF), a major cardiovascular disorder, remains a grievous clinical condition regardless of advances in medical care. Hyponatremia is classified as a serum sodium concentration of <135 mEq/L, and the prevalence, clinical impact and prognostic factor of hyponatremia in heart failure patients varies widely. The current study was conducted with the aim of assessing the prevalence of hyponatremia in patients hospitalized with a diagnosis of HF and comparing baseline clinical characteristic of HF patients based on their sodium status. Survival difference between patients with hyponatremia and normonatremia was also assessed and the clinical prognostic indicators of overall mortality in HF patients were evaluated.
Original languageEnglish
Article numbere0207242
JournalPloS ONE
Issue number11
Publication statusPublished - 8 Nov 2018

Data Availability Statement

All relevant data are within the paper and its Supporting Information files.


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