The spectrum of 5-fluorouracil cardiotoxicity

Jonathan R. Dalzell, Leslie M. Samuel

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


Cardiotoxicity is a rare but serious complication of 5-fluorouracil therapy. Coronary vasospasm and, less frequently, acute myocarditis have been identified as underlying mechanisms. We report a case of severe toxicity in a relatively young and fit male patient being treated for metastatic colonic adenocarcinoma displaying characteristics that cannot be explained by either mechanism alone. Anti-Cancer Drugs 20:79-80

Original languageEnglish
Pages (from-to)79-80
Number of pages2
JournalAnti-Cancer Drugs
Issue number1
Publication statusPublished - Jan 2009


  • Cardiomyopathy
  • Cardiotoxicity
  • Chemotherapy
  • Fluorouracil
  • Ischaemia


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