The worm profits from undercharging

Ian Stansfield, Christopher G Proud

Research output: Contribution to journalArticle


Hypoxia endangers the survival of cells and organisms. Mutations in an enzyme that attaches amino acids to tRNAs to supply protein synthesis confer resistance to hypoxia in C. elegans. By slowing down protein synthesis (a major consumer of energy), such mutations may save valuable energy and/or prevent accumulation of malfolded proteins.
Original languageEnglish
Pages (from-to)309-310
Number of pages2
JournalCell Metabolism
Issue number4
Publication statusPublished - 8 Apr 2009


  • animals
  • Caenorhabditis elegans
  • cell hypoxia
  • protein biosynthesis
  • thermodynamics


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