Abstract
BACKGROUND: Several studies on various bariatric surgeries involving patients with type 2 diabetes mellitus (T2DM) showed an overall rate of remission of hyperglycemia. However, there is little known about predictive factors on remission after different types of surgeries. The aim of this study was to identify the T2DM remission rate and to determine the effects of preoperative factors characteristics of remission of type 2 diabetes in Iran.
METHODS: We conducted a retrospective analysis of 1351 patients with T2DM operated by three different types of surgeries (Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and One Anastomosis Gastric Bypass (OAGB)). Diabetes remission was defined according to the American Diabetes Association (ADA) criteria. Binary logistic regression analyses were employed.
RESULTS: A total of 1351 patients, 675 patients (50.0%) undergoing OAGB, 475 (35.2%) RYGB, and 201 (14.9%) SG. 80.6%, 84.2% of OAGB, 81.7%, 82.6% of RYGB, and 77.1%, 81.5% of SG participants were in T2DM remission after 1 and 3 years, respectively. 1- and 3-year remission were associated with preoperative age, duration of T2DM, FBS and HbA1c, BMI, insulin therapy, and a family history of obesity (p < 0.05).
CONCLUSION: The remission of T2DM after RYGB, SG, and OAGB surgery is dependent on various preoperative factors. Patients with younger age, shorter duration of T2DM, lower preoperative HbA1c and FBS, higher BMI, who were not on insulin therapy, and not having a family history of obesity were the best candidates to achieve a prolonged diabetes remission.
| Original language | English |
|---|---|
| Article number | 260 |
| Number of pages | 9 |
| Journal | BMC Endocrine Disorders |
| Volume | 22 |
| Issue number | 1 |
| Early online date | 26 Oct 2022 |
| DOIs | |
| Publication status | Published - 26 Oct 2022 |
Bibliographical note
AcknowledgementsThe authors would like to thank the staff at the Minimally Invasive Surgery Research Center (MISRC) in Rasoul-e-Akram Hospital.
Funding Information:
This study was supported by the Deputy of Research of Iran University of Medical Sciences, Tehran, Iran.
Keywords
- Humans
- Gastric Bypass/methods
- Diabetes Mellitus, Type 2/surgery
- Obesity, Morbid/surgery
- Retrospective Studies
- Glycated Hemoglobin A
- Weight Loss
- Gastrectomy/methods
- Bariatric Surgery
- Obesity/surgery
- Insulins
- Treatment Outcome
Access to Document
- Moradi_etal_BMCED_Type_2_Diabetes_VoR
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