UK national survey of the management of vaginal intraepithelial neoplasia

Mahalakshmi Gurumurthy* (Corresponding Author), Simon Leeson, John Tidy, Margaret E. Cruickshank

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Vaginal intraepithelial neoplasia (VaIN) is less common than intraepithelial neoplasia at other non-cervical sites and can be challenging to manage. This survey describes current clinical practice by colposcopists in the UK. An online questionnaire was emailed to all the lead colposcopists in U.K. A total of 86 (43%) responses were obtained. The median number of cases of VaIN seen in a year was five (range 0–100. Most clinics (95%) managed low grade VaIN conservatively. Local vaginal mucosal excision was the most common surgical procedure. Half of respondents adopted observation, although 64% of the units referred cases to a cancer centre. More than half used a combination of cytology and colposcopy for follow-up; only two reported using Human papilloma virus testing. Seventy-seven of eighty-six lead colposcopists did not have a local guideline and would support national guidance. Treatment differed across the UK with no agreed management guidelines.
Original languageEnglish
Pages (from-to)694-698
Number of pages5
JournalJournal of Obstetrics and Gynaecology
Issue number5
Early online date14 Oct 2019
Publication statusPublished - Jul 2020


  • Vaginal intraepithelial neoplasia
  • management
  • vaginectomy
  • guidelines


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