Clare Adam

2020

Ovine prenatal growth-restriction and sex influence fetal adipose tissue phenotype and impact postnatal lipid metabolism and adiposity in vivo from birth until adulthood

Wallace, J. M., Milne, J. S., Aitken, B. W., Aitken, R. P. & Adam, C. L., 14 Feb 2020, In: PloS ONE. 15, 2, 27 p., e0228732.

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12 Citations (Scopus)

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2018

Ovine prenatal growth restriction impacts glucose metabolism and body composition throughout life in both sexes

Wallace, J. M., Milne, J. S., Aitken, R. P., Horgan, G. W. & Adam, C. L., 1 Aug 2018, In: Reproduction. 156, 2, p. 103-119 17 p.

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15 Citations (Scopus)

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2017

Impact of donor and recipient adiposity on placental and fetal growth in adolescent sheep

Wallace, J. M., Milne, J. S., Adam, C. L. & Aitken, R. P., Apr 2017, In: Reproduction. 153, 4, p. 381-394 14 p.

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5 Citations (Scopus)

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2016

Effects of Dietary Fibre (Pectin) and/or Increased Protein (Casein or Pea) on Satiety, Body Weight, Adiposity and Caecal Fermentation in High Fat Diet-Induced Obese Rats

Adam, C. L., Gratz, S. W., Peinado, D. I., Thomson, L. M., Garden, K. E., Williams, P. A., Richardson, A. J. & Ross, A. W., 25 May 2016, In: PloS ONE. 11, 5, 16 p., e0155871.

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60 Citations (Scopus)

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Epigenetics and developmental programming of welfare and production traits in farm animals

Sinclair, K. D., Rutherford, K. M. D., Wallace, J. M., Brameld, J. M., Stoger, R., Alberio, R., Sweetman, D., Gardner, D. S., Perry, V. E. A., Adam, C. L., Ashworth, C. J., Robinson, J. E. & Dwyer, C. M., 2016, In: Reproduction, Fertility and Development. 28, 10, p. 1443-1478 36 p.

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80 Citations (Scopus)

16 Downloads (Pure)

2015

Soluble Fermentable Dietary Fibre (Pectin) Decreases Caloric Intake, Adiposity and Lipidaemia in High-Fat Diet-Induced Obese Rats

Adam, C. L., Thomson, L. M., Williams, P. A. & Ross, A. W., 8 Oct 2015, In: PloS ONE. 10, 10, e0140392.

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44 Citations (Scopus)

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Orexigenic Gene Expression in Late Gestation Ovine Foetal Hypothalamus is Sensitive to Maternal Undernutrition and Realimentation

Adam, C. L., Williams, P. A., Milne, J. S., Aitken, R. P. & Wallace, J. M., Oct 2015, In: Journal of Neuroendocrinology. 27, 10, p. 765-771 7 p.

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7 Citations (Scopus)

12 Downloads (Pure)

Undernutrition and stage of gestation influence fetal adipose tissue gene expression

Wallace, J. M., Milne, J. S., Aitken, R. P., Redmer, D. A., Reynolds, L. P., Luther, J. S., Horgan, G. W. & Adam, C. L., 1 Jun 2015, In: Journal of Molecular Endocrinology. 54, 3, p. 263-275 13 p.

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22 Citations (Scopus)

8 Downloads (Pure)

Dose-dependent effects of a soluble dietary fibre (pectin) on food intake, adiposity, gut hypertrophy and gut satiety hormone secretion in rats

Adam, C. L., Williams, P. A., Garden, K. E., Thomson, L. M. & Ross, A. W., 20 Jan 2015, In: PloS ONE. 10, 1, 14 p., 0115438.

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57 Citations (Scopus)

9 Downloads (Pure)

2014

Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats

Adam, C. L., Williams, P. A., Dalby, M. J., Garden, K., Thomson, L. M., Richardson, A. J., Gratz, S. W. & Ross, A. W., 22 Aug 2014, In: Nutrition & Metabolism. 11, 36.

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83 Citations (Scopus)

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Influence of birth weight and gender on lipid status and adipose tissue gene expression in lambs

Wallace, J. M., Milne, J. S., Aitken, R. P. & Adam, C. L., 1 Aug 2014, In: Journal of Molecular Endocrinology. 53, 1, p. 131-144 14 p.

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22 Citations (Scopus)

Impact of embryo donor adiposity, birthweight and gender on early postnatal growth, glucose metabolism and body composition in the young lamb

Wallace, J. M., Milne, J. S., Aitken, R. P. & Adam, C. L., Jun 2014, In: Reproduction, Fertility and Development. 26, 5, p. 665-681 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Citations (Scopus)

2013

Impact of birth weight and gender on early postnatal hypothalamic energy balance regulatory gene expression in the young lamb

Adam, C. L., Bake, T., Findlay, P. A., Milne, J. S., Aitken, R. P. & Wallace, J. M., Nov 2013, In: International Journal of Developmental Neuroscience. 31, 7, p. 608-615 8 p.

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15 Citations (Scopus)

4 Downloads (Pure)

2012

In vivo changes in central and peripheral insulin sensitivity in a large animal model of obesity

Adam, C. L., Findlay, P. A., Aitken, R. P., Milne, J. S. & Wallace, J. M., Jul 2012, In: Endocrinology. 153, 7, p. 3147-3157 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Citations (Scopus)

Adverse metabolic phenotype in low-birth-weight lambs and its modification by postnatal nutrition

Wallace, J. M., Milne, J. S., Adam, C. L. & Aitken, R. P., 28 Feb 2012, In: British Journal of Nutrition. 107, 4, p. 510-522 13 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

2011

Effects of altered glucose supply and adiposity on expression of hypothalamic energy balance regulatory genes in late gestation growth restricted ovine fetuses

Adam, C. L., Bake, T., Findlay, P., Milne, J. S., Aitken, R. P. & Wallace, J. M., Nov 2011, In: International Journal of Developmental Neuroscience. 29, 7, p. 775-781 7 p.

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10 Citations (Scopus)

Adiposity and plane of nutrition influence reproductive neuroendocrine and appetite responses to intracerebroventricular insulin and neuropeptide-Y in sheep

Miller, D. W., Bennett, E. J., Harrison, J. L., Findlay, P. & Adam, C. L., Jan 2011, In: Reproduction, Fertility and Development. 23, 2, p. 329-338 10 p.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

2010

Decreased blood-brain leptin transfer in an ovine model of obesity and weight loss: resolving the cause of leptin resistance

Adam, C. & Findlay, P., Jun 2010, In: International Journal of Obesity. 34, 6, p. 980-988 9 p.

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Leptin: primary central site of action?

Adam, C. L., May 2010, In: Endocrinology. 151, 5, p. 1975-1977 3 p.

Research output: Contribution to journal › Article › peer-review

2008

Maternal nutrition and the programming of obesity: The brain

Mühlhäusler, B. S., Adam, C. L. & McMillen, I. C., Jul 2008, In: Organogenesis. 4, 3, p. 144-152 9 p.

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Expression of energy balance regulatory genes in the developing ovine fetal hypothalamus at midgestation and the influence of hyperglycemia

Adam, C. L., Findlay, P. A., Chanet, A., Aitken, R. P., Milne, J. S. & Wallace, J. M., Jun 2008, In: American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 294, 6, p. R1895-R1900 6 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Reduced blood-brain leptin signalling in obesity and after slimming: Lessons from sheep

Adam, C. L., Findlay, P. A., Forno, S. J. & Petrie, A. W., May 2008, In: Proceedings of the Nutrition Society. 67, OCE8, p. E384 1 p.

Research output: Contribution to journal › Article › peer-review

Photoperiod influences the central effects of ghrelin on food intake, GH and LH secretion in sheep

Harrison, J. L., Miller, D. W., Findlay, P. A. & Adam, C. L., Apr 2008, In: Neuroendocrinology. 87, 3, p. 182-192 11 p.

Research output: Contribution to journal › Article

51 Citations (Scopus)

2007

Nutritional Influences on Reproductive Neuroendocrine Output: Insulin, Leptin, and Orexigenic Neuropeptide Signaling in the Ovine Hypothalamus

Miller, D. W., Harrison, J. L., Bennett, E. J., Findlay, P. & Adam, C. L., 1 Nov 2007, In: Endocrinology. 148, 11, p. 5313-5322 10 p.

Research output: Contribution to journal › Article

20 Citations (Scopus)

An immunohistochemical study of the localization and developmental expression of ghrelin and its functional receptor in the ovine placenta

Harrison, J. L., Adam, C. L., Brown, Y. A., Wallace, J. M., Aitken, R. P., Lea, R. G. & Miller, D. W., 27 Jun 2007, In: Reproductive Biology and Endocrinology. 5, 8 p., 25.

Research output: Contribution to journal › Article

34 Citations (Scopus)

2006

Blood-brain leptin transport and appetite and reproductive neuroendocrine responses to intracerebroventricular leptin injection in sheep: Influence of photoperiod: Influence of photoperiod

Adam, C. L., Findlay, P. A. & Miller, D. W., Oct 2006, In: Endocrinology. 147, 10, p. 4589-4598 10 p.

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Increased maternal nutrition alters development of the appetite-regulating network in the brain

Muhlhausler, B. S., Adam, C. L., Findlay, P. A., Duffield, J. A. & McMillen, I. C., Jun 2006, In: The FASEB Journal. 20, 8, p. 1257-1259 3 p.

Research output: Contribution to journal › Article › peer-review

192 Citations (Scopus)

Blood-brain transport of leptin: influence of photoperiod and leptinaemia in sheep

Adam, C. L., Findlay, P. A., Bennett, E. J., Harrison, L. K. & Miller, D. W., 2006, In: Proceedings of the Nutrition Society. 65, Supplement, p. 68A 1 p.

Research output: Contribution to journal › Article › peer-review

Insulin blood-brain transport and appetite responses to central insulin infusion in sheep

Bennett, E. J., Harrison, J. L., Findlay, P. A., Miller, D. W. & Adam, C. L., 2006, In: Proceedings of the Nutrition Society. 65, Supplement, p. 69A 1 p.

Research output: Contribution to journal › Article › peer-review

2005

The ovarian expression of mRNAs for aromatase, IGF-1 receptor, IGF-binding protein-2, -4 and -5, leptin and leptin receptor in cycling ewes after three days of leptin infusion

Munoz-Gutierrez, M., Findlay, P. A., Adam, C. L., Wax, G., Campbell, B. K., Kendall, N. R., Khalid, M., Forsberg, M. & Scaramuzzi, R. J., Dec 2005, In: Reproduction. 130, 6, p. 869-881 13 p.

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation

Muhlhausler, B. S., Adam, C. L., Marrocco, E. M., Findlay, P. A., Roberts, C. T., McFarlane, J. R., Kauter, K. G. & McMillen, I. C., 15 May 2005, In: The Journal of Physiology. 565, 1, p. 185-195 11 p.

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Hypothalamic responses to peripheral glucose infusion in food-restricted sheep are influenced by photoperiod

Archer, Z. A., Rhind, S. M., Findlay, P. A., Kyle, C. E., Barber, M. C. & Adam, C. L., Mar 2005, In: Journal of Endocrinology. 184, 3, p. 515-525 11 p.

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Expression of orexin receptors in the brain and peripheral tissues of the male sheep

Zhang, S., Blache, D., Vercoe, P. E., Adam, C. L., Blackberry, M. A., Eidne, K. A., Martin, G. B. & Findlay, P. A., 15 Jan 2005, In: Regulatory Peptides. 124, 1-3, p. 81-87 7 p.

Research output: Contribution to journal › Article › peer-review

83 Citations (Scopus)

Immunohistochemical evidence for an endocrine/paracrine role for ghrelin in the reproductive tissues of sheep

Miller, D. W., Harrison, J. L., Brown, Y. A., Doyle, U., Lindsay, A., Adam, C. L. & Lea, R. G., 2005, In: Reproductive Biology and Endocrinology. 3, 14 p.

Research output: Contribution to journal › Article

69 Citations (Scopus)

Rumen microbial population dynamics in response to photoperiod

McEwan, N. R., Abecia, L., Regensbogenova, M., Adam, C. L., Newbold, C. J. & Findlay, P. A., 2005, In: Letters in Applied Microbiology. 41, 1, p. 97-101 5 p.

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

2004

Effects of nutritional status and gonadal steroids on expression of appetite-regulatory genes in the hypothalamic arcuate nucleus of sheep

Archer, Z. A., Findlay, P. A., McMillen, S. R., Rhind, S. M. & Adam, C. L., Sept 2004, In: Journal of Endocrinology. 182, 3, p. 409-419 11 p.

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Appetite regulation and seasonality

Adam, C. L. & Mercer, J., Aug 2004, In: Proceedings of the Nutrition Society. 63, 3, p. 413-419 7 p.

Research output: Contribution to journal › Article › peer-review

53 Citations (Scopus)

Appetite regulatory neuropeptides are expressed in the sheep hypothalamus before birth

Muhlhausler, B. S., McMillen, I. C., Rouzaud, G., Findlay, P. A., Marrocco, E. M., Rhind, S. M. & Adam, C. L., Jun 2004, In: Journal of Neuroendocrinology. 16, 6, p. 502-507 6 p.

Research output: Contribution to journal › Article › peer-review

59 Citations (Scopus)

Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus, is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression

Tups, A., Ellis, C., Moar, K-M., Logie, T., Adam, C. L., Mercer, J. & Klingenspor, M., 1 Mar 2004, In: Endocrinology. 145, 3, p. 1185-1193 9 p.

Research output: Contribution to journal › Article › peer-review

90 Citations (Scopus)

Glucose increases the expression of POMC mRNA in the hypothalamus of the fetal sheep in late gestation

Muhlhausler, B. S., Adam, C. L., Findlay, P. A., Marrocco, E. & McMillen, I. C., Feb 2004, In: Journal of the Society for Gynecologic Investigation. 11, 2 Supplement, p. 113A 1 p.

Research output: Contribution to journal › Article › peer-review

2003

Early regulation of hypothalamic arcuate nucleus CART gene expression by short photoperiod in the Siberian hamster

Mercer, J., Ellis, C., Moar, K-M., Logie, T., Morgan, P. J. & Adam, C. L., 28 Mar 2003, In: Regulatory Peptides. 111, 1-3, p. 129-136 8 p.

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Leptin actions on the reproductive neuroendocrine axis in sheep

Adam, C. L., Archer, Z. A. & Miller, D. W., 2003, In: Reproduction Supplement. 61, p. 283-297 15 p.

Research output: Contribution to journal › Article

33 Citations (Scopus)

2002

Hypothalamic gene expression in sheep for cocaine- and amphetamine-regulated transcript, pro-opiomelanocortin, neuropeptide Y, agouti-related peptide and leptin receptor and responses to negative energy balance

Adam, C. L., Archer, Z. A., Findlay, P., Thomas, L. & Marie, M., Apr 2002, In: Neuroendocrinology. 75, 4, p. 250-256 7 p.

Research output: Contribution to journal › Article › peer-review

88 Citations (Scopus)

Leptin secretion and hypothalamic neuropeptide and receptor gene expression in sheep

Sorensen, A., Adam, C. L., Findlay, P., Marie, M., Thomas, L., Travers, M. T. & Vernon, R. G., Apr 2002, In: American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 282, 4, 9 p.

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Orexin gene expression and regulation by photoperiod in the sheep hypothalamus

Archer, Z. A., Findlay, P. A., Rhind, S. M., Mercer, J. G. & Adam, C. L., 15 Mar 2002, In: Regulatory Peptides. 104, 1-3, p. 41-45 5 p.

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Contrasting effects of different levels of food intake and adiposity on LH secretion and hypothalamic gene expression in sheep

Archer, Z. A., Rhind, S. M., Findlay, P. A., Kyle, C. E., Thomas, L., Marie, M. & Adam, C. L., 2002, In: Journal of Endocrinology. 175, 2, p. 383-393 11 p.

Research output: Contribution to journal › Article › peer-review