P06-20 Characterisation of the effects of Ketoconazole and Diethylstilbestrol on the human fetal adrenal

L. L. Lecante; P. Lelandais; S. Mazaud-Guittot; P. A. Fowler

doi:10.1016/j.toxlet.2022.07.338

P06-20 Characterisation of the effects of Ketoconazole and Diethylstilbestrol on the human fetal adrenal

L. L. Lecante, P. Lelandais, S. Mazaud-Guittot, P. A. Fowler

Universite de Rennes

Research output: Contribution to journal › Abstract › peer-review

Abstract

A woman's reproductive lifespan is largely programmed during her fetal life when crucial morphogenetic events for establishment of the ovarian reserve occur. Although an increasing body of evidence suggests that exposures to endocrine disrupting chemicals (EDCs) during specific windows of sensitivity can result in reproductive disorders, underlying mechanisms remain poorly understood...

Original language	English
Pages (from-to)	S120
Number of pages	1
Journal	Toxicology Letters
Volume	368
Issue number	Supplement 1
DOIs	https://doi.org/10.1016/j.toxlet.2022.07.338
Publication status	Published - 1 Sept 2022
Event	XVIth International Congress of Toxicology: UNITING IN TOXICOLOGY - Maastricht, Netherlands Duration: 18 Sept 2022 → 21 Sept 2022 Conference number: 16 https://www.ict2022.com/

Bibliographical note

This work was supported by the European Union's Horizon 2020 FREIA project (grant agreement No. 825100).

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10.1016/j.toxlet.2022.07.338

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title = "P06-20 Characterisation of the effects of Ketoconazole and Diethylstilbestrol on the human fetal adrenal",

abstract = "A woman's reproductive lifespan is largely programmed during her fetal life when crucial morphogenetic events for establishment of the ovarian reserve occur. Although an increasing body of evidence suggests that exposures to endocrine disrupting chemicals (EDCs) during specific windows of sensitivity can result in reproductive disorders, underlying mechanisms remain poorly understood...",

author = "Lecante, {L. L.} and P. Lelandais and S. Mazaud-Guittot and Fowler, {P. A.}",

note = "This work was supported by the European Union's Horizon 2020 FREIA project (grant agreement No. 825100).; XVIth International Congress of Toxicology : UNITING IN TOXICOLOGY, ICT 2022 ; Conference date: 18-09-2022 Through 21-09-2022",

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T1 - P06-20 Characterisation of the effects of Ketoconazole and Diethylstilbestrol on the human fetal adrenal

AU - Lecante, L. L.

AU - Lelandais, P.

AU - Mazaud-Guittot, S.

AU - Fowler, P. A.

N1 - Conference code: 16

PY - 2022/9/1

Y1 - 2022/9/1

N2 - A woman's reproductive lifespan is largely programmed during her fetal life when crucial morphogenetic events for establishment of the ovarian reserve occur. Although an increasing body of evidence suggests that exposures to endocrine disrupting chemicals (EDCs) during specific windows of sensitivity can result in reproductive disorders, underlying mechanisms remain poorly understood...

AB - A woman's reproductive lifespan is largely programmed during her fetal life when crucial morphogenetic events for establishment of the ovarian reserve occur. Although an increasing body of evidence suggests that exposures to endocrine disrupting chemicals (EDCs) during specific windows of sensitivity can result in reproductive disorders, underlying mechanisms remain poorly understood...

U2 - 10.1016/j.toxlet.2022.07.338

DO - 10.1016/j.toxlet.2022.07.338

M3 - Abstract

SN - 0378-4274

VL - 368

SP - S120

JO - Toxicology Letters

JF - Toxicology Letters

IS - Supplement 1

T2 - XVIth International Congress of Toxicology

Y2 - 18 September 2022 through 21 September 2022

ER -

P06-20 Characterisation of the effects of Ketoconazole and Diethylstilbestrol on the human fetal adrenal

Abstract

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