Aberdeen Birth Cohort Study 1936 (ABC 1936)

Research output

Research output per year 2010 2011 2012 2014 2022

• 32 Article

Research output per year

Research output per year

Search results

• 2022

  Cognitive Test Scores and Progressive Cognitive Decline in the Aberdeen 1921 and 1936 Birth Cohorts

  Whalley, L. J., Staff, R. T., Lemmon, H., Fox, H. C., McNeil, C. & Murray, A. D., 1 Mar 2022, In: Brain Sciences. 12, 3, 19 p., 318.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cognitive Dysfunction 100%
  • Parturition 84%
  • Dementia 63%
  • Verbal Learning 40%
  • Age of Onset 14%
  1 Citation (Scopus)

  12 Downloads (Pure)
• 2017

  Childhood intelligence and personality traits neuroticism and openness contributes to social mobility: A study in the Aberdeen 1936 Birth Cohort

  Staff, R. T., Hogan, M. J. & Whalley, L. J., Aug 2017, In: Personality and Individual Differences. 114, p. 206-212 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Social Mobility 100%
  • Neuroticism 73%
  • neuroticism 67%
  • Intelligence 65%
  • personality traits 57%
  9 Citations (Scopus)

  15 Downloads (Pure)

• Klotho, APOEε4, cognitive ability, brain size, atrophy and survival: A study in the Aberdeen Birth Cohort of 1936

  de Vries, C. F., Staff, R. T., Harris, S. E., Chapko, D., Williams, D. S., Reichert, P., Ahearn, T., McNeil, C. J., Whalley, L. J. & Murray, A. D., Jul 2017, In: Neurobiology of Aging. 55, p. 91-98 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Heterozygote 100%
  • Atrophy 81%
  • Parturition 65%
  • Aptitude 63%
  • Cognition 55%
  18 Citations (Scopus)

  15 Downloads (Pure)

• A comparison of measurement methods of hippocampal atrophy rate for predicting Alzheimer's dementia in the Aberdeen Birth Cohort of 1936

  Rana, A. K., Sandu, A-L., Robertson, K. L., McNeil, C. J., Whalley, L. J., Staff, R. T. & Murray, A. D., 2017, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 6, p. 31-39 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atrophy 100%
  • Alzheimer Disease 89%
  • Parturition 79%
  • Neuroimaging 34%
  • ROC Curve 32%
  12 Citations (Scopus)

  16 Downloads (Pure)
• 2016

  Late-life deficits in cognitive, physical and emotional functions, childhood intelligence and occupational profile: a life-course examination of the Aberdeen 1936 Birth Cohort (ABC1936)

  Chapko, D., Staff, R. T., McNeil, C. J., Whalley, L. J., Black, C. & Murray, A. D., Jul 2016, In: Age and Ageing. 45, 4, p. 486-493 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Intelligence 100%
  • Cognition 74%
  • Parturition 65%
  • Occupations 46%
  • Structural Models 18%
  13 Citations (Scopus)

• Brain hyperintensity location determines outcome in the triad of impaired cognition, physical health and depressive symptoms: A cohort study in late life

  Murray, A., McNeil, C., Salarirad, S., Deary, I., Phillips, L., Whalley, L. & Staff, R., Mar 2016, In: Archives of Gerontology and Geriatrics. 63, p. 49-54 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • cognitive ability 100%
  • brain 98%
  • cognition 95%
  • Cognition 92%
  • Cohort Studies 79%
  16 Citations (Scopus)

  12 Downloads (Pure)

• Cerebral correlates of cognitive reserve

  Whalley, L. J., Staff, R. T., Fox, H. C. & Murray, A. D., 30 Jan 2016, In: Psychiatry Research. 247, p. 65-70 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cognitive Reserve 100%
  • Dementia 42%
  • Cerebrovascular Disorders 35%
  • Brain 25%
  • Pathology 21%
  26 Citations (Scopus)

  14 Downloads (Pure)
• 2014

  Structural brain complexity and cognitive decline in late life: A longitudinal study in the Aberdeen 1936 Birth Cohort

  Sandu-Giuraniuc, A-L., Staff, R. T., McNeil, C. J., Mustafa, N., Ahearn, T., Whalley, L. J. & Murray, A. D., 15 Oct 2014, In: Neuroimage. 100, p. 558-563 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Longitudinal Studies 100%
  • Cognitive Dysfunction 98%
  • Parturition 83%
  • Aptitude 70%
  • White Matter 62%
  39 Citations (Scopus)

  14 Downloads (Pure)

• Functional gene group analysis indicates no role for heterotrimeric G proteins in cognitive ability

  Hill, W. D., de Leeuw, C., Davies, G., Liewald, D. C. M., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Starr, J. M., Pendleton, N., Posthuma, D., Bates, T. C. & Deary, I. J., 13 Mar 2014, In: PloS ONE. 9, 3, 8 p., e91690.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Heterotrimeric GTP-Binding Proteins 100%
  • Aptitude 50%
  • Intelligence 47%
  • Genes 30%
  • Single Nucleotide Polymorphism 25%
  2 Citations (Scopus)

  11 Downloads (Pure)

• Early Life Socioeconomic Circumstance and Late Life Brain Hyperintensities: A Population Based Cohort Study

  Murray, A. D., McNeil, C. J., Salarirad, S., Whalley, L. J. & Staff, R. T., 18 Feb 2014, In: PloS ONE. 9, 2, 7 p., e88969.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • brain 100%
  • childhood 81%
  • dementia 79%
  • cardiovascular disease 49%
  • cognitive factors 45%
  24 Citations (Scopus)

  8 Downloads (Pure)

• Physical capability and subsequent positive mental wellbeing in older people: findings from five HALCyon cohorts

  Cooper, R., Stafford, M., Hardy, R., Aihie Sayer, A., Ben-Shlomo, Y., Cooper, C., Craig, L., Deary, I. J., Gallacher, J., McNeill, G., Starr, J. M., Kuh, D., Gale, C. R. & on behalf of the HALCyon study team, Feb 2014, In: Age. 36, 1, p. 445-456 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Healthy Aging 100%
  • Hand Strength 41%
  • Neuroticism 23%
  • Body Size 23%
  • Walking 17%
  22 Citations (Scopus)

  17 Downloads (Pure)

• Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

  Hill, W. D., Davies, G., Van De Lagemaat, L. N., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S., Espeseth, T., & 7 othersLundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C. & Deary, I. J., 7 Jan 2014, In: Translational Psychiatry. 4, p. 1-8 8 p., e341.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Guanylate Kinases 100%
  • Intelligence 69%
  • N-Methyl-D-Aspartate Receptors 66%
  • Genetic Variation 63%
  • Aptitude 44%
  46 Citations (Scopus)

• Polygenic risk for Alzheimer's disease is not associated with cognitive ability or cognitive aging in non-demented older people

  Harris, S. E., Davies, G., Luciano, M., Payton, A., Fox, H. C., Haggarty, P., Ollier, W., Horan, M., Porteous, D. J., Starr, J. M., Whalley, L. J., Pendleton, N. & Deary, I. J., 1 Jan 2014, In: Journal of Alzheimer's Disease. 39, 3, p. 565-574 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cognitive Aging 100%
  • dementia 72%
  • cognitive ability 72%
  • Alzheimer Disease 56%
  • Aptitude 49%
  37 Citations (Scopus)

  9 Downloads (Pure)

• A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing

  Davies, G., Harris, S. E., Reynolds, C. A., Payton, A., Knight, H. M., Liewald, D. C. M., Lopez, L. M., Luciano, M. C., Gow, A. J., Corley, J., Henderson, R. D., Murray, C. L., Pattie, A., Fox, H. C., Redmond, P., Lutz, M. W., Chiba-Falek, O., Linnertz, C., Saith, S., Haggarty, P., & 15 othersMcNeill, G., Ke, X., Ollier, W., Horan, M., Roses, A. D., Ponting, C. P., Porteous, D. J., Tenesa, A., Pickles, A., Starr, J. M., Whalley, L. J., Pedersen, N. L., Pendleton, N., Visscher, P. M. & Deary, I. J., Jan 2014, In: Molecular Psychiatry. 19, 1, p. 76-87 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Aging 100%
  • Apolipoproteins E 76%
  • Genome-Wide Association Study 75%
  • Mitochondrial Membranes 50%
  • Single Nucleotide Polymorphism 22%
  131 Citations (Scopus)
• 2013

  Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme

  Hardy, R., Cooper, R., Sayer, A. A., Ben-Shlomo, Y., Cooper, C., Deary, I. J., Demakakos, P., Gallacher, J., Martin, R. M., McNeill, G., Starr, J. M., Steptoe, A., Syddall, H., Kuh, D. & HALCyon Study Team, 20 Feb 2013, In: PloS ONE. 8, 2, 13 p., e56483.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Physical Functional Performance 100%
  • Muscle Strength 93%
  • Hand Strength 71%
  • Body Mass Index 65%
  • Cohort Studies 62%
  132 Citations (Scopus)

  12 Downloads (Pure)

• Depressive symptoms in late life and cerebrovascular disease: the importance of intelligence and lesion location

  Murray, A. D., Staff, R. T., McNeil, C. J., Salarirad, S., Phillips, L. H., Starr, J., Deary, I. J. & Whalley, L. J., Jan 2013, In: Depression and Anxiety. 30, 1, p. 77-84 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Intelligence 100%
  • Cerebrovascular Disorders 98%
  • intelligence 74%
  • Depression 62%
  • brain 59%
  12 Citations (Scopus)
• 2012

  Cognitive function in childhood and lifetime cognitive change in relation to mental wellbeing in four cohorts of older people

  HALCyon Study Team, 10 Sept 2012, In: PloS ONE. 7, 9, 9 p., e44860.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cognition 100%
  • Aptitude 86%
  • Personality 18%
  • Parturition 14%
  • Healthy Aging 13%
  46 Citations (Scopus)

  11 Downloads (Pure)

• Brain structural complexity and life course cognitive change

  Mustafa, N., Ahearn, T. S., Waiter, G. D., Murray, A. D., Whalley, L. J. & Staff, R. T., 2 Jul 2012, In: Neuroimage. 61, 3, p. 694-701 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fractals 100%
  • Brain 37%
  • Intelligence 30%
  • White Matter 25%
  • Cognitive Aging 13%
  49 Citations (Scopus)

• Childhood socioeconomic status and adult brain size: Childhood socioeconomic status influences adult hippocampal size

  Staff, R. T., Murray, A. D., Ahearn, T. S., Mustafa, N., Fox, H. C. & Whalley, L. J., May 2012, In: Annals of Neurology. 71, 5, p. 653-660 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Social Class 100%
  • Brain 51%
  • Dementia 29%
  • Aptitude 23%
  • Education 22%
  134 Citations (Scopus)

• Brain lesions, hypertension and cognitive aging in the 1921 and 1936 Aberdeen birth cohorts

  Murray, A. D., Staff, R. T., McNeil, C. J., Salarirad, S., Starr, J. M., Deary, I. J. & Whalley, L. J., Apr 2012, In: Age. 34, 2, p. 451-459 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Aging 100%
  • Intelligence 69%
  • White Matter 65%
  • Parturition 50%
  • Hypertension 46%
  25 Citations (Scopus)

• Genetic contributions to stability and change in intelligence from childhood to old age

  Deary, I. J., Yang, J., Davies, G., Harris, S. E., Tenesa, A., Liewald, D., Luciano, M., Lopez, L. M., Gow, A. J., Corley, J., Redmond, P., Fox, H. C., Rowe, S. J., Haggarty, P., McNeill, G., Goddard, M. E., Porteous, D. J., Whalley, L. J., Starr, J. M. & Visscher, P. M., 9 Feb 2012, In: Nature. 482, 7384, p. 212-215 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Intelligence 100%
  • Single Nucleotide Polymorphism 47%
  • Cognitive Aging 26%
  • Healthy Aging 23%
  • Linkage Disequilibrium 21%
  210 Citations (Scopus)
• 2011

  The balance between cognitive reserve and brain imaging biomarkers of cerebrovascular and Alzheimer's diseases

  Murray, A. D., Staff, R. T., McNeil, C. J., Salarirad, S., Ahearn, T. S., Mustafa, N. & Whalley, L. J., Dec 2011, In: Brain. 134, 12, p. 3687-3696 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Reserve 100%
  • Cerebrovascular Disorders 70%
  • Neuroimaging 61%
  • Alzheimer Disease 52%
  • Biomarkers 44%
  94 Citations (Scopus)

• Inter-individual differences in fMRI entropy measurements in old age

  Sokunbi, M. O., Staff, R. T., Waiter, G. D., Ahearn, T. S., Fox, H. C., Deary, I. J., Starr, J. M., Whalley, L. J. & Murray, A. D., Nov 2011, In: IEEE Transactions on Biomedical Engineering. 58, 11, p. 3206-3214 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic Resonance Imaging 100%
  • Entropy 73%
  • Inspection 44%
  44 Citations (Scopus)

• Factors associated with symptoms of anxiety and depression in five cohorts of community-based older people: the HALCyon (Healthy Ageing across the Life Course) Programme

  Gale, C. R., Sayer, A. A., Cooper, C., Dennison, E. M., Starr, J. M., Whalley, L. J., Gallacher, J. E., Ben-Shlomo, Y., Kuh, D., Hardy, R., Craig, L. C., Deary, I. J. & The HALCyon Study Team, Oct 2011, In: Psychological Medicine. 41, 10, p. 2057-2073 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Healthy Aging 100%
  • Anxiety 57%
  • Depression 52%
  • anxiety 50%
  • Cognition 15%
  55 Citations (Scopus)

• Genome-wide association studies establish that human intelligence is highly heritable and polygenic

  Davies, G., Tenesa, A., Payton, A., Yang, J., Harris, S. E., Liewald, D., Ke, X., Le Hellard, S., Christoforou, A., Luciano, M., McGhee, K., Lopez, L., Gow, A. J., Corley, J., Redmond, P., Fox, H. C., Haggarty, P., Whalley, L. J., McNeill, G., Goddard, M. E., & 12 othersEspeseth, T., Lundervold, A. J., Reinvang, I., Pickles, A., Steen, V. M., Ollier, W., Porteous, D. J., Horan, M., Starr, J. M., Pendleton, N., Visscher, P. M. & Deary, I. J., Oct 2011, In: Molecular Psychiatry. 16, 10, p. 996-1005 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Intelligence 100%
  • Genome-Wide Association Study 98%
  • Single Nucleotide Polymorphism 34%
  • Genetic Variation 26%
  • Individuality 26%
  470 Citations (Scopus)

• How the 1932 and 1947 mental surveys of Aberdeen schoolchildren provide a framework to explore the childhood origins of late onset disease and disability

  Whalley, L. J., Murray, A. D., Staff, R. T., Starr, J. M., Deary, I. J., Fox, H. C., Lemmon, H., Duthie, S. J., Collins, A. R. & Crawford, J. R., Aug 2011, In: Maturitas. 69, 4, p. 365-372 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Late Onset Disorders 100%
  • Dementia 62%
  • Parturition 51%
  • Nutrigenomics 36%
  • Cohort Studies 33%
  40 Citations (Scopus)

• Cerebellar brain volume accounts for variance in cognitive performance in older adults

  Hogan, M. J., Staff, R. T., Bunting, B. P., Murray, A. D., Ahearn, T. S., Deary, I. J. & Whalley, L. J., Apr 2011, In: Cortex. 47, 4, p. 441-450 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cerebellum 100%
  • brain 91%
  • Frontal Lobe 68%
  • Brain 53%
  • performance 50%
  61 Citations (Scopus)

• Childhood socioeconomic position and objectively measured physical capability levels in adulthood: a systematic review and meta-analysis

  Birnie, K., Cooper, R., Martin, R. M., Kuh, D., Sayer, A. A., Alvarado, B. E., Bayer, A., Christensen, K., Cho, S., Cooper, C., Corley, J., Craig, L., Deary, I. J., Demakakos, P., Ebrahim, S., Gallacher, J., Gow, A. J., Gunnell, D., Haas, S., Hemmingsson, T., & 18 othersInskip, H., Jang, S., Noronha, K., Osler, M., Palloni, A., Rasmussen, F., Santos-Eggimann, B., Spagnoli, J., Starr, J., Steptoe, A., Syddall, H., Tynelius, P., Weir, D., Whalley, L. J., Zunzunegui, M. V., Ben-Shlomo, Y., Hardy, R. & HALCyon Study Team, 26 Jan 2011, In: PloS ONE. 6, 1, 13 p., e15564.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Walking Speed 100%
  • Meta-Analysis 85%
  • Systematic Reviews 84%
  • Hand Strength 60%
  • Research Personnel 40%
  111 Citations (Scopus)

  12 Downloads (Pure)

• How useful are the SF-36 sub-scales in older people? Mokken scaling of data from the HALCyon programme

  Mishra, G. D., Gale, C. R., Sayer, A. A., Cooper, C., Dennison, E. M., Whalley, L. J., Craig, L. C. A., Kuh, D., Deary, I. J. & The HALCyon Study Team, 2011, In: Quality of Life Research. 20, 7, p. 1005-1010 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Healthy Aging 100%
  • scaling 83%
  • Psychometrics 74%
  • Mental Health 62%
  • Parturition 55%
  24 Citations (Scopus)
• 2010

  Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking

  Haggarty, P., Hoad, G., Harris, S. E., Starr, J. M., Fox, H. C., Deary, I. J. & Whalley, L. J., 25 Jun 2010, In: PloS ONE. 5, 6, 6 p., e11329.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Methyltransferases 100%
  • Intelligence 94%
  • Epigenomics 78%
  • DNA 50%
  • Genes 36%
  27 Citations (Scopus)

  12 Downloads (Pure)

• Caffeine, cognition, and socioeconomic status

  Kyle, J., Fox, H. C. & Whalley, L. J., 2010, In: Journal of Alzheimer's Disease. 20, S1, p. S151-S159 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Caffeine 100%
  • dementia 96%
  • Social Class 90%
  • cognition 77%
  • Cognition 75%
  10 Citations (Scopus)

• Solvent exposure and cognitive ability at age 67: a follow-up study of the 1947 Scottish Mental Survey

  Dick, F. D., Bourne, V., Semple, S., Fox, H. C., Miller, B., Deary, I. & Whalley, L. J., 2010, In: Occupational and Environmental Medicine. 67, 6, p. 401-407 7 p.

  Research output: Contribution to journal › Article › peer-review

  • cognitive ability 100%
  • Aptitude 68%
  • Trail Making Test 57%
  • Cognition 45%
  • Verbal Learning 37%
  6 Citations (Scopus)