Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re: Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9

Thomas B L Lam; Richard J Sylvester; Steven E Canfield; Lorenzo Marconi; Steven MacLennan; Yuhong Yuan; Muhammad Imran Omar; James N'Dow

doi:10.1016/j.eururo.2017.04.008

Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re: Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9

Thomas B L Lam, Richard J Sylvester, Steven E Canfield, Lorenzo Marconi, Steven MacLennan, Yuhong Yuan, Muhammad Imran Omar, James N'Dow

Research output: Contribution to journal › Letter › peer-review

Abstract

We would like to thank Drs. Dahm, Narayan, and Jung for their thoughtful and well-argued comments on our paper [1]. However, it would appear that they have misinterpreted the main point of the article, which is to help guideline developers resolve conflicting findings between large, multicentre, and robust randomized controlled trials (RCTs) and those of systematic reviews and meta-analyses (MA). This issue goes beyond “conflicting results of different studies” within MAs, especially when the MA largely consists of small, underpowered, heterogeneous studies with a high risk of bias and/or poor reporting.

Original language	English
Pages (from-to)	e93-e94
Number of pages	2
Journal	European Urology
Volume	72
Issue number	4
Early online date	17 Apr 2017
DOIs	https://doi.org/10.1016/j.eururo.2017.04.008
Publication status	Published - Oct 2017

Keywords

Letter

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Lam, T. B. L., Sylvester, R. J., Canfield, S. E., Marconi, L., MacLennan, S., Yuan, Y., Omar, M. I., & N'Dow, J. (2017). Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re: Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9. European Urology, 72(4), e93-e94. https://doi.org/10.1016/j.eururo.2017.04.008

Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re: Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9. / Lam, Thomas B L; Sylvester, Richard J; Canfield, Steven E et al.
In: European Urology, Vol. 72, No. 4, 10.2017, p. e93-e94.

Research output: Contribution to journal › Letter › peer-review

Lam, TBL, Sylvester, RJ, Canfield, SE, Marconi, L, MacLennan, S, Yuan, Y, Omar, MI & N'Dow, J 2017, 'Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re: Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9', European Urology, vol. 72, no. 4, pp. e93-e94. https://doi.org/10.1016/j.eururo.2017.04.008

Lam TBL, Sylvester RJ, Canfield SE, Marconi L, MacLennan S, Yuan Y et al. Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re: Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9. European Urology. 2017 Oct;72(4):e93-e94. Epub 2017 Apr 17. doi: 10.1016/j.eururo.2017.04.008

Lam, Thomas B L ; Sylvester, Richard J ; Canfield, Steven E et al. / Reply to Philipp Dahm, Vikram Narayan, and Jae Hung Jung's Letter to the Editor re : Richard J. Sylvester, Steven E. Canfield, Thomas B.L. Lam, et al. Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree. Eur Urol 2017;71:811-9. In: European Urology. 2017 ; Vol. 72, No. 4. pp. e93-e94.

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